Establishment of monoclonal antibody mNI-11 which induces homotypic cell aggregation of LPS-treated U937 cells.
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چکیده
منابع مشابه
Regulation of CD43-induced U937 homotypic aggregation.
CD43 (leukosialin, sialophorin), a prominent component of the hemopoietic cell surface, has an enigmatic role in cell-cell interaction. The observation that CD43 ligation triggers homotypic aggregation of monoblastoid U937 cells has permitted analysis of this: CD43-induced aggregation was distinguishable from CD29- (also known as beta1 integrin) or CD98- (also known as 4F2, or fusion-related pr...
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Treatment of human monocytes for 24-48 h with the anti-CD43 mAb L10 caused five- to sevenfold stimulation of hydrogen peroxide-producing capacity, an established characteristic of activated monocytes. Peroxide-producing capacity induced by L10 antibody (1.6 +/- 0.3 nmol H2O2/micrograms DNA/h) was comparable with that induced by IFN-gamma (1.3 +/- 0.4 nmol H2O2/micrograms DNA/h), but appeared mo...
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متن کاملThe functional interactions between CD98, b1-integrins, and CD147 in the induction of U937 homotypic aggregation
CD98 is expressed on both hematopoietic and nonhematopoietic cells and has been implicated in a variety of different aspects of cell physiology and immunobiology. In this study, the functional interactions between CD98 and other adhesion molecules on the surface of the promonocyte line U937 are examined by means of a quantitative assay of cell aggregation. Several of the CD98 antibodies induced...
متن کاملThe functional interactions between CD98, beta1-integrins, and CD147 in the induction of U937 homotypic aggregation.
CD98 is expressed on both hematopoietic and nonhematopoietic cells and has been implicated in a variety of different aspects of cell physiology and immunobiology. In this study, the functional interactions between CD98 and other adhesion molecules on the surface of the promonocyte line U937 are examined by means of a quantitative assay of cell aggregation. Several of the CD98 antibodies induced...
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ژورنال
عنوان ژورنال: Nippon Saikingaku Zasshi
سال: 1993
ISSN: 1882-4110,0021-4930
DOI: 10.3412/jsb.48.739